The nucleolus through the years

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The nucleolus through the years

At present it is clear that nucleoli are multifunctional cell organelles and participate in the cell proliferation, resting state, differentiation, maturation, aging and death. Therefore, they also represent very useful morphological markers of these cell states under physiological, pathological and experimental conditions. One of important nucleolar functions related to the mentioned cell stat...

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The nucleolus.

When cells are observed by phase contrast microscopy, nucleoli are among the most conspicuous structures. The nucleolus was formally described between 1835 and 1839, but it was another century before it was discovered to be associated with a specific chromosomal locus, thus defining it as a cytogenetic entity. Nucleoli were first isolated in the 1950s, from starfish oocytes. Then, in the early ...

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ژورنال

عنوان ژورنال: Journal of Applied Biomedicine

سال: 2011

ISSN: 1214-021X,1214-0287

DOI: 10.2478/v10136-011-0010-7